Psychopathology - The Evolving Science of Mental Disorder

The scientific study of mental disorder is exciting today because of discoveries in molecular genetics, cognitive processes, neurochemistry and neuroanatomy. The study of mental disorder has evolved from a primarily descriptive discipline into a mature science that encompasses both biological underpinnings and social and developmental work. Psychopathology combines these fields of research to present a comprehensive picture of psychosis. In this important volume, distinguished investigators from these fields present findings from their laboratories, as well as perspectives on areas of rapid growth and change. The editors also provide thoughtful overviews of four major topics in psychopathology research: brain mechanisms, thinking, development and genetics. This book will appeal to graduate students, clinicians and researchers in the fields of psychiatry, cognitive science and neuroscience. Contents
List of contributors
Preface Steven Matthysse
Part I. Brain Mechanisms: 1. Editors introduction: from controversy to connectivity Francine M. Benes
2. The functional parcellation of dorsolateral prefrontal cortex and the heterogeneous facets of schizophrenia Patricia Goldman-Rakic
3. Components of working memory deficit in schizophrenia Sohee Park and Gillian ODriscoll
4. Temporal lobe structural abnormalities in schizophrenia: a selective review and presentation of new magnetic resonance findings Martha E. Shenton
5. Location, location, location: the pathway from behavior to brain locus in schizophrenia Deborah L. Levy
6. The defects of affect and attention in schizophrenia: a possible neuroanatomical substrate Francine M. Benes
Part II. Development: 7. Editors introduction: methods in the developmental study of madness Jerome Kagan
8. Developmental psychopathology: from attribution toward information Sheldon H. White
Comments Philip S. Holzman
9. A paradoxical partnership: some historical and contemporary referents linking adult schizophreniform disorder and resilient children under stress Norman Garmezy
10. A look at the evolution of developmental models of schizophrenia L. Erlenmeyer-Kimling
11. Developmental theory: lessons from the study of risk and psychopathology Dante Cicchetti
12. The return of the ancients: on temperament and development Jerome Kagan
Part III. Thinking: 13. Editors introduction: Upward toward phenomenology m downward toward physiology Steven Matthysse
14. The psychometric assessment of schizophrenia proneness Jean P. Chapman and Loren J. Chapman
15. Politeness in schizophrenia Roger Brown
Comments Philip S. Holzman
16. Neuroleptic treatment effects in relation to psychotherapy, social skills training and social withdrawal in schizophrenics Herbert E. Spohn
Comments Philip S. Holzman
17. Familial factors in the impairment of attention in schizophrenia: data from Ireland, Israel and the District of Columbia Allan F. Mirsky
18. Parsing cognitive processes: psychopathological and neurophysiological constraints Anne Sereno
19. Cognitive psychopathology in schizophrenia: explorations in language, memory, associations and movements Brendan A. Maher
Part IV. Genetics: 20. Editors introduction: contemporary issues in the genetics of psychopathological disorders Deborah L. Levy, Steven Matthysse and Philip S. Holzman
21. Genetic and environmental factors in the etiology of schizophrenia Seymour S. Kety
22. Problems and paradoxes in research on the etiology of schizophrenia Einar Kringlen
Comments Philip S. Holzman and Steven Matthysse
23. Epistemological issues in psychiatric research Josef Parnas
24. Searching for major genes in schizophrenia Kenneth K. Kidd
25. The Drosophila eye and the genetics of schizophrenia Steven Matthysse
Part V. Response and Reflections: 26. Reflections on the developing science of psychopathology Philip S. Holzman
Author index
Subject index.

Author/Editor Details
Edited by: Steven Matthysse, Harvard University, Massachusetts
Edited by: Francine M. Benes, McClean Hospital
Edited by: Deborah L. Levy, Harvard University, Massachusetts
Edited by: Jerome Kagan, Harvard University, Massachusetts