The book is very different from any science book. Darwin is not lecturing from the podium of an auditorium. He's your learned friend sitting in the easy chair next to yours, probably in front of a cheerful fire after a nice dinner, telling you about some really interesting things he's seen and ideas he's had. Much of it is written in first person, which is very refreshing and personal.
It's clear that Darwin is multiple kinds of a genius. He's a lucid writer, with concise and telling expressions: he never uses two words if there's a single better one. He's also a gifted experimenter. He refers in many places to decades of clever experiments he's done with pigeons, bees, ants, grass, flowers, and other organisms, and you get the definite impression that these are only the tip of the iceberg of his accomplishments. Besides his deliberate experiments, he's also an amazing observational naturalist. He alludes to many things that he himself has witnessed, not only on his famous voyage around South America, but also on trips around England and Europe. In addition, he's an exhaustive and thorough researcher. The first part of the book is a review of everything (and I mean everything) written to that point on the subject. It's obvious that he's read everything available on the topic. Finally, he is an active correspondent with everyone doing related work or research at the time. He quotes the research and observations of numerous others, from some of the most famous scientists of his time to ordinary farmers who raise crops and animals for a living.
He begins by discussing the variations possible among members of the same species that are easily observable and are obviously deliberate, namely among domesticated animals and plants. This makes it clear that significant differences within a species are possible during only a few generations. This is what he calls "selection": deliberately choosing animals and plants for definite features, and encouraging these features.
He then expands his view to look at variation within nature, outside domestication. This allows him to bring up "natural selection": the conditions of nature favoring certain features over others. Organisms with good features are more likely to survive and reproduce. Organisms with bad features are unlikely to reproduce, and may become extinct.
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